Abstract
The hydrodehalogenation of 2-chloro-, 2-bromo-, 3-bromo, and 3,5-dibromopyridine has been studied in the presence of a palladium complex catalyst immobilized on silica gel, and a Pd/C catalyst. Cleavage of bromine from bromopyridines over the Pd complex is significantly faster than from the bromo-substituted furanes and thiophenes previously studied. Debromination over Pd/C is faster than over the complex catalyst. Over both catalysts 3-bromopyridine debrominates faster than the 2-isomer. When molecular deuterium is used, the respective deuterated pyridines can be obtained.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature cited
V. Z. Sharf, L. I. Belen'kii, A. S. Gurovets, and I. B. Karmanova, Khim. Geterotsikl. Soedin., No. 2, 176 (1982).
V. Z. Sharf, S. Z. Taits, A. S. Gurovets, Yu. B. Vol'kenshtein, B. P. Fabrichnyi, and S. I. Sherbakova, Khim. Geterotsikl. Soedin., No. 2, 171 (1982).
V. Z. Sharf, A. S. Gurovets, I. B. Slinyakova, L. P. Finn, L. Kh. Freidlin, and V. N. Krutii, Izv. Akad. Nauk SSSR, Ser. Khim., No. 1, 114 (1980).
V. Z. Sharf, A. S. Gurovets, I. B. Slinyakova, L. P. Finn, L. Kh. Freidlin, and V. N. Krutii, Izv. Akad. Nauk SSSR, Ser. Khim., No. 1, 104 (1979).
R. E. Lokhov, S. S. Lokhova, N. M. Gaidarova, and L. I. Belen'kii, Khim. Geterotsikl. Soedin., No. 9, 1236 (1981).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1229–1232, September, 1985.
Rights and permissions
About this article
Cite this article
Gurovets, A.S., Sharf, V.Z. & Belen'kii, L.I. Hydrodehalogenation of bromo- and chloropyridines over palladium complex and palladium metal catalysts. Chem Heterocycl Compd 21, 1023–1025 (1985). https://doi.org/10.1007/BF00515028
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00515028