Chemistry of Heterocyclic Compounds

, Volume 22, Issue 3, pp 265–267 | Cite as

Nucleophilic substitution reactions in 4-halonitro-pyrazolecarboxylic acids

  • Yu. A. Manaev
  • V. P. Perevalov
  • M. A. Andreeva
  • B. I. Stepanov


The reaction of 4-bromo-1-methyl-3-nitropyrazole-5- and 4-bromo-1-methyl-5-nitro-pyrazole-3-carboxylic acids with arylamines in aqueous solution in the presence of monovalent copper salts leads to the formation of 4-arylamino- and 4-hydroxy substituted nitropyrazolecarboxylic acids.


Copper Aqueous Solution Organic Chemistry Nucleophilic Substitution Substitution Reaction 


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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • Yu. A. Manaev
    • 1
  • V. P. Perevalov
    • 1
  • M. A. Andreeva
    • 1
  • B. I. Stepanov
    • 1
  1. 1.D. I. Mendeleev Chemical Technology InstituteMoscow

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