Advertisement

Chemistry of Heterocyclic Compounds

, Volume 22, Issue 3, pp 265–267 | Cite as

Nucleophilic substitution reactions in 4-halonitro-pyrazolecarboxylic acids

  • Yu. A. Manaev
  • V. P. Perevalov
  • M. A. Andreeva
  • B. I. Stepanov
Article

Abstract

The reaction of 4-bromo-1-methyl-3-nitropyrazole-5- and 4-bromo-1-methyl-5-nitro-pyrazole-3-carboxylic acids with arylamines in aqueous solution in the presence of monovalent copper salts leads to the formation of 4-arylamino- and 4-hydroxy substituted nitropyrazolecarboxylic acids.

Keywords

Copper Aqueous Solution Organic Chemistry Nucleophilic Substitution Substitution Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    A. N. Kost and I. I. Grandberg, Adv. Heterocycl. Chem., 6, 347 (1966).Google Scholar
  2. 2.
    M. D. Coburn, J. Heterocycl. Chem., 8, 153 (1971).Google Scholar
  3. 3.
    C. G. Newton, W. D. Ollis, and D. E. Wright, J. Chem. Soc., Perkin 1, 63 (1984).Google Scholar
  4. 4.
    R. G. Johnes, J. Amer. Chem. Soc., 71, 3994 (1949).Google Scholar
  5. 5.
    M. A. Khan and A. A. Pinto, J. Heterocycl. Chem., 18, 9 (1981).Google Scholar
  6. 6.
    S. F. Vasilevskii, E. M. Rubinshtein, and M. S. Shvartsberg, Izv. Akad. Nauk SSSR, Ser. Khim., 1175 (1978).Google Scholar
  7. 7.
    Yu. A. Manaev, V. P. Perevalov, M. A. Andreeva, and B. I. Stepanov, Khim. Geterotsikl. Soed., No. 8, 1123, (1984).Google Scholar
  8. 8.
    E. S. Krongaus, D. A. Bochvar, I. V. Stankevich, and V. V. Korshak, Dokl. Akad. Nauk SSSR, Ser. Khim, 179, 94 (1968).Google Scholar
  9. 9.
    Yu. A. Manaev, M. A. Andreeva, V. P. Perevalov, and B. I. Stepanov, Zh. Org. Khim., 52, 2592 (1982).Google Scholar

Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • Yu. A. Manaev
    • 1
  • V. P. Perevalov
    • 1
  • M. A. Andreeva
    • 1
  • B. I. Stepanov
    • 1
  1. 1.D. I. Mendeleev Chemical Technology InstituteMoscow

Personalised recommendations