Abstract
The chemical transformations of 5-alkyl-2-thioxopyrrolidines with nucleophilic and electrophilic reagents were studied and compared with the reactivities of their oxygen analogs. On the basis of the experimental data obtained from alkylation, hydroxyethylation, and condensation reactions it was established that, depending on the conditions and the character of the reagent, 5-alkyl-2-thioxopyrrolidines undergo the indicated reactions in the thiolactam or thiolactin form.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1648–1651, December, 1979
Original article submitted November 25, 1978.
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Bespalova, G.V., Sedavkina, V.A. & Kharchenko, V.G. Reactivities of 5-alkyl-2-thioxopyrrolidines. Chem Heterocycl Compd 15, 1323–1327 (1979). https://doi.org/10.1007/BF00514735
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DOI: https://doi.org/10.1007/BF00514735