Chemistry of Heterocyclic Compounds

, Volume 20, Issue 8, pp 918–920 | Cite as

Synthesis of 9-chloropyrazolo[4,3-b]quinolines

  • Yu. A. Manaev
  • V. P. Perevalov
  • M. A. Andreeva
  • B. I. Stepanov


A series of 1-methyl-4-arylaminopyrazole-3- and -5-carboxylic acids were synthesized by the reaction of 1-methyl-4-halopyrazole-3- and -5-carboxylic acids with aromatic amines in the presence of a copper catalyst; treatment with phosphorus oxychloride converted them to the corresponding 9-chlorosubstituted 1-methyl-1H- and 2-methyl-2H-pyrazolo[4,3-b]quinolines.


Copper Phosphorus Organic Chemistry Carboxylic Acid Quinoline 
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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Yu. A. Manaev
    • 1
  • V. P. Perevalov
    • 1
  • M. A. Andreeva
    • 1
  • B. I. Stepanov
    • 1
  1. 1.D. I. Mendeleev Moscow Chemical Technology InstituteMoscow

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