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Bromination of 4-(2-thienyl)thiazoles and 2-(2-thienyl)quinoline

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Depending on the substituent, the bromination of 4-(2-thienyl)thiazoles and 2-(2-thienyl)quinoline takes place in the 5 position of the thiophene or thiazole ring. When an amino group is present in the 2 position of the thiazole ring, bromination takes place in the 5 position of the thiazole ring. When excess brominating agent is present, a second bromine atom enters the 5 position of the free ring.

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Authors and Affiliations

  1. Kuibyshev Polytechnic Institute, 443645, Kuibyshev

    V. A. Smirnov, A. V. Zimichev, G. A. Lyzhova & A. E. Lipkin

Authors
  1. V. A. Smirnov
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  2. A. V. Zimichev
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  3. G. A. Lyzhova
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  4. A. E. Lipkin
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 35–38, January, 1982.

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Smirnov, V.A., Zimichev, A.V., Lyzhova, G.A. et al. Bromination of 4-(2-thienyl)thiazoles and 2-(2-thienyl)quinoline. Chem Heterocycl Compd 18, 28–31 (1982). https://doi.org/10.1007/BF00513284

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  • DOI: https://doi.org/10.1007/BF00513284

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