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2-Amino-Δ2-thiazolin-4-ones in acylation reactions

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It is shown that 2-acetyl derivatives are formed in the acetylation of 2-amino-Δ2-thiazolin-4-one and its 2-phenyl analog with acetic anhydride in acetic acid. 2-Am-ino-Δ2-thiazolin-4-one is not acetylated by acetyl chloride in the presence of alkaline agents, while 2-phenylamino-Δ2-thiazolin-4-one gives a 3-acetyl derivative. In both cases in the acetylation of 2-phenylamino-Δ2-thiazolin-4-one a 3,4-diacetyl derivative is formed along with a monoacetylation product. The structures of the compounds obtained were confirmed by their IR, PMR, UV, and mass spectra.

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Authors and Affiliations

  1. Lensovet Leningrad Technological Institute, 198013, Leningrad

    S. M. Ramsh, Yu. G. Basova, A. I. Ginak, N. A. Smorygo & A. A. Rodin

Authors
  1. S. M. Ramsh
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  2. Yu. G. Basova
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  3. A. I. Ginak
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  4. N. A. Smorygo
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  5. A. A. Rodin
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 30–34, January, 1982.

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Ramsh, S.M., Basova, Y.G., Ginak, A.I. et al. 2-Amino-Δ2-thiazolin-4-ones in acylation reactions. Chem Heterocycl Compd 18, 24–28 (1982). https://doi.org/10.1007/BF00513283

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  • DOI: https://doi.org/10.1007/BF00513283

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