Abstract
The acidities of two series of substituted 1- and 2-tetrazolylacetic acids, as well as some 1- and 2-substituted 5-tetrazolylacetic acids, in water and 50% ethanol were investigated. All of the investigated compounds are stronger acids than acetic acid and are comparable to haloacetic acids. The induction constants (σI) of the 1-, 2-, and 5-tetrazolyl groups (0.65, 0.62, and 0.41, respectively) were calculated from data on the acidities of tetrazolylacetic acids.
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See [1] for communication 10.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 264–266, February, 1982.
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Poplavskii, V.S., Ostrovskii, V.A., Koldobskii, G.I. et al. Tetrazoles. 11. Acidities of tetrazolylacetic acids. Chem Heterocycl Compd 18, 208–211 (1982). https://doi.org/10.1007/BF00512972
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DOI: https://doi.org/10.1007/BF00512972