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Catalytic reductive debromination — A new method for the preparation of deutero-substituted thiophenes and furans

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The principles of the reductive dehalogenation of a number of mono- and dibromosubstituted functional derivatives of thiophene and furan in the presence of a palladium complex applied to silica gel modified with γ-aminopropyl groups were investigated. A one-step method for the preparation of mono- and dideutero-substituted carbonyl compounds of the furan and thiophene series was developed.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 176–180, February, 1982.

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Sharf, V.Z., Belen'kii, L.I., Gurovets, A.S. et al. Catalytic reductive debromination — A new method for the preparation of deutero-substituted thiophenes and furans. Chem Heterocycl Compd 18, 134–138 (1982). https://doi.org/10.1007/BF00512954

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  • DOI: https://doi.org/10.1007/BF00512954

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