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Chemistry of Heterocyclic Compounds

, Volume 19, Issue 1, pp 103–106 | Cite as

Synthesis of indole derivatives of pyrido[2,3-d]pyrimidine

  • T. V. Stupnikova
  • T. V. Nuzhnaya
  • N. A. Klyuev
  • A. Yu. Chervinskii
Article

Abstract

Recyclization of the pyrimidine ring with inclusion of the reagent in the newly formed ring to give indole derivatives of 2,3-disubstituted pyridines occurs in the reaction of the anhydro base of 4-(3-indolyl)pyrimidine with CH acids in the presence of triethylamine. The products react with formamide to give the pyrido[2,3-d]pyrimidine heterocyclic system.

Keywords

Organic Chemistry Pyridine Indole Pyrimidine Formamide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • T. V. Stupnikova
    • 1
  • T. V. Nuzhnaya
    • 1
  • N. A. Klyuev
    • 1
  • A. Yu. Chervinskii
    • 1
  1. 1.Donetsk State UniversityDonetsk

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