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New method for the synthesis of some polyfunctional 5-aminopyrimidines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A preparative method for the synthesis of some 5-aminopyrimidines, which consists in the nucleophilic opening of the oxazole ring of 2,5-dimethyl-7-chloro- and 7-amino-substituted oxazole[5,4-d]pyrimidines under the influence of acids and bases, was developed.

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Literature cited

  1. R. Elderfield (editor), Heterocyclic Compounds, Vol. 6, Wiley (1957).

  2. R. G. Melik-Organdzhanyan and T. A. Khachaturyan, USSR Inventor's Certificate No. 810699; Byull. Izobret., No. 9, 92 (1981).

  3. R. G. Melik-Organdzhanyan, T. A. Khachaturyan, Zh. S. Manukyan, Dzh. G. Amiragov, and S. A. Papoyan, Arm., Khim. Zh., No. 4, 324 (1981).

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  4. R. Elderfield (editor), Heterocyclic Compounds, Vol. 5, Wiley (1957).

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Authors and Affiliations

  1. A. L. Mndzhoyan Institute of Fine Organic Chemistry, 375014, Yerevan

    R. G. Melik-Organdzhanyan, T. A. Khachaturyan, V. S. Mirzoyan & F. G. Arsenyan

Authors
  1. R. G. Melik-Organdzhanyan
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  2. T. A. Khachaturyan
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  3. V. S. Mirzoyan
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  4. F. G. Arsenyan
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 112–114, January, 1983.

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Melik-Organdzhanyan, R.G., Khachaturyan, T.A., Mirzoyan, V.S. et al. New method for the synthesis of some polyfunctional 5-aminopyrimidines. Chem Heterocycl Compd 19, 100–103 (1983). https://doi.org/10.1007/BF00512826

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  • DOI: https://doi.org/10.1007/BF00512826

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