Abstract
In a study of the possibilities of a simple method for the preparation of 3-indolylglyoxals two new methods for the synthesis of indolylglyoxal structures were proposed. The first method consists in oxidation of 3-hydroxyacetylindole with the dimethyl sulfoxide-oxalyl chloride complex, but for a number of reasons it is virtually inapplicable to the preparation of substituted indolylglyoxals. In the second case the readily synthesized 3-indolylglyoxyl chlorides are reduced to the corresponding aldehydes in good yields by means of trialkyltin hydrides.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 46–48, January, 1983.
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Vereshchagin, A.L., Bryanskii, O.V. & Semenov, A.A. New syntheses of 3-indolylglyoxal. Chem Heterocycl Compd 19, 40–42 (1983). https://doi.org/10.1007/BF00512812
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DOI: https://doi.org/10.1007/BF00512812