Summary
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1.
The radioprotective activity of several hundreds of fermentation liquids have been examined by methods described in our previous reports.
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2.
Out of the tested fermentation liquids, good protective ability was rendered—mainly after acid hydrolysis—by the fermentation liquid of Penicillium notatum strain which is applied also in industry.
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3.
The agent, when it was produced, proved to be d-Penicillamine.
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4.
The radioprotective activity of d-Penicillamine as well as its ability to reduce the toxicity of nitrogen mustard have been compared with the effect of other wellknown radioprotectors, on an equimolar basis.
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5.
It was found that its protective ability for E. coli B against both X-ray and nitrogen mustard is about the same degree as that of cysteine.
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6.
From the results, theoretical and practical conclusions have been drawn.
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Hernádi, F., Békési, I., Nagy, Z. et al. The effect on escherichia coli B of “radioprotectors” produced by fermentation. Archiv. Mikrobiol. 44, 228–232 (1962). https://doi.org/10.1007/BF00510942
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DOI: https://doi.org/10.1007/BF00510942