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Evaluation of circulating immune complexes and antinuclear antibodies in Japanese patients with leprosy

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Summary

In 79 patients with leprosy a significant increase of anti-extractable nuclear antigen (ENA) antibodies and circulating immune complexes (CIC) was found. No correlation between CIC and anti-ENA antibodies was demonstrable. Since such a correlation is known from antinuclear antibodies and CIC in patients with systemic lupus erythematosus, it appears likely that anti-ENA antibodies do not play a causative role in CIC-mediated pathogenesis of leprosy.

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Authors and Affiliations

  1. Department of Pathology (Head: Prof. Y. Hamashima, MD), Faculty of Medicine, Kyoto University, 606, Sakyo, Kyoto, Japan

    F. Furukawa, K. Sekita & Y. Hamashima

  2. Department of Dermatology (Head: Prof. S. Imamura, MD), Faculty of Medicine, Kyoto University, 606, Sakyo, Kyoto, Japan

    M. Ozaki & S. Imamura

Authors
  1. F. Furukawa
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  2. K. Sekita
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  3. Y. Hamashima
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  4. M. Ozaki
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  5. S. Imamura
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Supported by a grant from the Ministry of Education, Science, and Culture of Japan

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Furukawa, F., Sekita, K., Hamashima, Y. et al. Evaluation of circulating immune complexes and antinuclear antibodies in Japanese patients with leprosy. Arch Dermatol Res 275, 144–146 (1983). https://doi.org/10.1007/BF00510043

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  • DOI: https://doi.org/10.1007/BF00510043

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