Summary
Dielectrophoretic experiments on pearlchain formation and collection of human melanocytes were performed as a function of the frequency of the applied nonuniform electric field. Evidence is reported showing that the behavior of malignant melanocytes is markedly dependent upon the type of established cell line (pigmented or achromic), age, and drug treatment (e.g., chlorpromazine).
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References
Aubert C, Rougé F, Galindo IR (1980) Tumorigenicity of human malignant melanocytes in nude mice in relation to their differentiation in vitro. J Natl Cancer Inst 64:1029–1040
Griffin JL, Stowell RE (1966) Orientation of Euglena by radiofrequency fields. Exp Cell Res 44:684–688
Lamprecht I, Mischel M (1981) Dielektrophoretische Untersuchungen an biologischen Systemen. Naturwissenschaften 68:501–506
Mischel M, Lamprecht I (1980) Dielectrophorectic rotation in budding yeast cells. Z Naturforsch [C] 35:1111–1113
Mischel M, Lamprecht I, Reichert U (1981) Dielectrophoresis — Foundations and applications. In: Preece AW, Light PA (eds) Cell electrophoresis. Elsevier/North-Holland Biomedical Press, Amsterdam
Pohl HA (1978) Dielectrophoresis — The behavior of neutral matter in nonuniform electric fields. Cambridge University Press, Cambridge
Zimmermann U, Scheurich P, Pilwat G, Benz R (1981) Cells with manipulated functions — New perspectives for cell biology, medicine, and technology. Angew Chem [Engl] 20:325–344
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This work was supported in part by grants from I.N.S.E.R.M. (ATP 67.78.79) and C.N.R. (P.V. Controllo Crescita Neplastica No. 80.01642.96)
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Mischel, M., Rougé, F., Lamprecht, I. et al. Dielectrophoresis of malignant human melanocytes. Arch Dermatol Res 275, 141–143 (1983). https://doi.org/10.1007/BF00510042
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DOI: https://doi.org/10.1007/BF00510042