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Chemistry of Heterocyclic Compounds

, Volume 7, Issue 9, pp 1173–1176 | Cite as

Investigations in the imidazole series

LXV. Synthesis of 2-aminoimidazole derivatives from 2-haloimidazoles
  • B. A. Priimenko
  • P. M. Kochergin
Article

Abstract

The reaction of 1-alkyl(hydroxyalkyl)-2-bromo-4,5-diphenylimidazoles with ammonia and primary and secondary amines was studied, and a new synthesis of 2-aminoimidazole derivatives was realized on the basis of 2-haloimidazoles. The starting compounds were obtained by the bromination of 1-alkyl(hydroxyalkyl)-4,5-diphenylimidazoles with bromine or by alkylation of 2-bromo-4,5-diphenylimidazole with alkyl halides, β -halo alcohols, and olefin oxides.

Keywords

Oxide Alcohol Ammonia Organic Chemistry Imidazole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • B. A. Priimenko
    • 1
    • 2
  • P. M. Kochergin
    • 1
    • 2
  1. 1.Zaporozhe State Medical InstituteUSSR
  2. 2.S. Ordzhonikidze All-Union Scientific-Research Institute of Pharmaceutical ChemistryMoscow

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