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Synthesis of 2-trichloromethyloxazolidin-5-ones by reaction of chloral with N,O-trimethylsilyl derivatives of amino acids

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The corresponding 2-trichloromethyloxazolidin-5-ones were obtained by reaction of chloral with trimethylsilyl (TMS) derivatives of some amino acids. The corresponding oxazolidin-5-ones could not be obtained by the action of chloral on aspartic and glutamic acids.

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Literature cited

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Authors and Affiliations

  1. Institute of Heteroorganic Compounds, Academy of Sciences of the USSR, 117813, Moscow

    Yu. A. Davidovich, L. A. Pavlova, A. Yu. Volkonskii & S. V. Rogozhin

Authors
  1. Yu. A. Davidovich
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  2. L. A. Pavlova
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  3. A. Yu. Volkonskii
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  4. S. V. Rogozhin
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1472–1473, November, 1978.

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Davidovich, Y.A., Pavlova, L.A., Volkonskii, A.Y. et al. Synthesis of 2-trichloromethyloxazolidin-5-ones by reaction of chloral with N,O-trimethylsilyl derivatives of amino acids. Chem Heterocycl Compd 14, 1194–1195 (1978). https://doi.org/10.1007/BF00509734

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  • DOI: https://doi.org/10.1007/BF00509734

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