Abstract
6-Aminouracils and N-substituted derivatives are cyanoacetylated to give 5-cyanoacetyl-6-aminouracils. In the presence of bases these are converted to pyrido[2,3-d]pyrimidine-2,4,5-triones in high yields.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 971–975, July, 1990.
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Smirnova, N.M., Cherdantseva, N.M., Burova, O.A. et al. Cyanoacetylation of 6-aminouracils. Synthesis of 7-aminopyrido[2,3-d]pyrimidine-2,4,5-triones. Chem Heterocycl Compd 26, 811–815 (1990). https://doi.org/10.1007/BF00509714
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DOI: https://doi.org/10.1007/BF00509714