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Treatment of cutaneous T-cell lymphoma with a new aromatic retinoid (Ro 10-9359)

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Summary

A 77-year-old woman developed a diffuse nodular eruption with histologic, ultrastructural, and biologic evidence of cutaneous T-cell lymphoma (CTCL) limited to the skin. She was treated with a new aromatic retinoid Ro 10-9359 (1 mg/kg/day). After 34 days, the lesions flattened completely and the mononuclear cell infiltrate decreased significantly. No clinical recurrences occured after a 4-month survey. Discontinuation of the aromatic retinoid led to a relapse with identical clinical and histologic features.

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Claudy, A.L., Delomier, Y. & Hermier, C. Treatment of cutaneous T-cell lymphoma with a new aromatic retinoid (Ro 10-9359). Arch Dermatol Res 273, 37–42 (1982). https://doi.org/10.1007/BF00509025

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