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Chemistry of Heterocyclic Compounds

, Volume 20, Issue 6, pp 697–699 | Cite as

Alkylation of 5-substituted tetrazoles with mannich bases

  • V. G. Kitaeva
  • R. I. Ishmetova
  • N. I. Latosh
  • N. M. Voronina
Article

Abstract

Mixtures of N(1) and N(2) isomers are formed in the alkylation of 1H-5-R-tetrazoles with N-(2-hydroxy-3-methoxy-5-formylbenzyl)piperidine, whereas primarily one of two possible N(1) or N(2) isomers is formed in the case of alkylation with N-(3,5-di-methyl-4-hydroxybenzyl)piperidine, depending on substituent R.

Keywords

Organic Chemistry Alkylation Tetrazoles Piperidine Mannich Base 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • V. G. Kitaeva
    • 1
  • R. I. Ishmetova
    • 1
  • N. I. Latosh
    • 1
  • N. M. Voronina
    • 1
  1. 1.Institute of Chemistry, Ural Science CenterAcademy of Sciences of the USSRSverdlovsk

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