Chemistry of Heterocyclic Compounds

, Volume 17, Issue 2, pp 124–125 | Cite as

Reaction of some benzoxazoline-2-thione derivatives with amines

  • K. Davidkov
  • D. Simov


Hydroxyphenylthioureas were obtained by the reaction of nitro, chloro, bromo, or amino derivatives of benzoxazoline-2-thiones with primary amines. If the substituent in the benzene ring is a nitro group, the reaction with certain secondary amines proceeds with the production of trisubstituted thioureas. It is shown that electron-acceptor substituents in the 5 and 6 positions of the benzene ring facilitate this reaction.


Benzene Organic Chemistry Thiourea Chloro Benzene Ring 
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Literature cited

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    K. Davidkov and D. C. Simov, C. R. Acad. Bulg. Sci., 26, 777 (1973).Google Scholar
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Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • K. Davidkov
    • 1
  • D. Simov
    • 1
  1. 1.K. Okhridskii Sofia UniversitySofiaBulgaria

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