Naunyn-Schmiedeberg's Archives of Pharmacology

, Volume 306, Issue 3, pp 301–304 | Cite as

A material with opioid activity in bovine milk and milk products

  • V. Brantl
  • H. Teschemacher
Short Communication

Summary

Chloroform-methanol extracts of lyophilized milk, of commercially available dried milk or baby food and of casein digests were tested for opioid activity on the guinea-pig ileum longitudinal muscle-myenteric plexus preparation. Compounds with opioid activity — which proved to be resistant to peptidases — were detected in certain batches of baby food, casein digest, and cow milk in considerably varying amounts.

Key words

Endorphins Opiate receptor ligands Pronase-resistant opioids Milk Baby food 

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • V. Brantl
    • 1
  • H. Teschemacher
    • 1
  1. 1.Department of NeuropharmacologyMax-Planck-Institut für PsychiatrieMünchen 40Federal Republic of Germany

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