Chemistry of Heterocyclic Compounds

, Volume 20, Issue 7, pp 761–766 | Cite as

Synthesis and properties of 1,2,2,6,6-pentamethyl-3,5-dimethylene-4-piperidone

  • A. M. Belostotskii
  • A. B. Shapiro


1,2,2,6,6-Pentamethyl-3,5-dimethylene-4-piperidone was synthesized, whereas analogous compounds in the 4-piperidone series could not be isolated. An unusual reaction of the compound obtained with primary aliphatic amines, consisting of successive addition of the amine at the C=C bonds, with a possible formation of an intermediate bicyclic adduct and further elimination of methylamine, was detected.


Organic Chemistry Adduct Methylamine Aliphatic Amine Successive Addition 
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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • A. M. Belostotskii
    • 1
    • 2
  • A. B. Shapiro
    • 1
    • 2
  1. 1.Scientific-Research Institute of PharmacologyAcademy of Medical Sciences of the USSRMoscow
  2. 2.Institute of Chemical PhysicsAcademy of Sciences of the USSRMoscow

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