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Chemistry of Heterocyclic Compounds

, Volume 20, Issue 7, pp 713–716 | Cite as

Synthesis and some electrophilic substitution reactions of 2-phenyloxazole

  • L. I. Belen'kii
  • M. A. Cheskis
Article

Abstract

A new synthesis of 2-phenyloxazole that includes the preparation of 2-phenyloxazoline and aromatization of the latter by the action of nickel peroxide was developed. It was established that under conditions that exclude protonation electrophilic substitution reactions are directed to the oxazole ring of 2-phenyloxazole; the 5 position is considerably more active than the 4 position.

Keywords

Nickel Peroxide Organic Chemistry Substitution Reaction Aromatization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • L. I. Belen'kii
    • 1
  • M. A. Cheskis
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRMoscow

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