Abstract
4,6-Dihydroxy-5-acetylpyrimidine was obtained by the solvolysis of 4,6-dialkoxy-5-acetylpyrimidines. The hydrolysis of 4,6-dichloro-5-acetylpyrimidine leads to opening of the heteroring to give s-cis,trans conformera of 2-cyano-3-hydroxy-2-buteneamide. 2′,4,6-Trihydroxy[4′,5]bipyrimidine was obtained by the condensation of 4,6-dialkoxy-5-acetylpyrimidines with benzalbisurea. It is shown that the products of the reaction of the same ketones with benzaldehyde in the presence of sodium alkoxides are derivatives of δ-diketones.
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See [1] for Communication 74.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 378–385, March, 1985.
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Mikhaleva, M.A., Repkova, M.N. & Mamaev, V.P. Pyrimidines. 75. Syntheses based on acetylpyrimidines. 4,6-Dihydroxy-5-acetylpyrimidine and preparation of 4′,5-bipyrimidines and their derivatives. Chem Heterocycl Compd 21, 315–322 (1985). https://doi.org/10.1007/BF00506674
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DOI: https://doi.org/10.1007/BF00506674