Summary
Five patients presenting clinically accepted sings of optic neuritis served as subjects for a study on EP's (evoked potentials); the patients were tested during the acute phase, the chronic phase and at a stage when no impairment was clinically observed.
At the acute phase of optic neuritis the VER was massively altered; in the chronic phase delayed latencies depending upon the impairment of visual acuity and visual fields could be recorded.
At the recovery stage, while visual acuity and visual field showed no deficit, not only delayed latencies but also reduction in the amplitude at all stimulation frequencies were recorded.
Zusammenfassung
Es wurden fünf Patienten, die klinisch alle Zeichen einer Neuritis nervi optici zeigten, mit der VER-Methode in drei verschiedenen Phasen der Affektion untersucht (Darbietung eines alternierenden Schachbrettmusters).
In der akuten Phase der Neuritis nervi optici, waren die EP (evozierte Potentiale) massiv reduziert, bei der chronisch verlaufenden Affektion konnte man verzögerte Latenzen registrieren, die ihrerseits von der Abnahme der Sehschärfe und von Gesichtsfeldausfällen abhängig waren. Bei den Patienten, die sich klinisch vollständig erholten (volle Sehschärfe, keine Gesichtsfelddefekte) war die Amplitude des VER in allen Stimulationsfrequenzen reduziert (10–30%), die Latenzen blieben deutlich verzögert.
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References
Adachi-Usami: Clinical evaluation of the V.E.R. in case of optic neuritis. Ophthal. Res. 4, 343–354 (1972/73)
Behrman, J., Nissim, S., Arden, G.B.: A clinical method for obtaining pattern V.E.R. Advanc. exp. Med. Biol. 24, 199–206
Halliday, A.M., McDonald, W.I., Mushin, J.: Delayed V.E.R. in optic neuritis. Lancet 1972 I, 982–985
Halliday, A.M., McDonald, W.I., Mushin, J.: V.E.R. in diagnosis of multiple sclerosis. Brit. med. J. 1973, 661–669
Halliday, A.M., McDonald, W.I., Mushin, J.: Delayed pattern evoked responses in optic neuritis in relation to visual acuity. Proc. ophthal. Soc. (U.K.) (1973)
Regan, D., Heron, J.R.: Clinical investigation of lesions of the visual pathway. A new objective technique. J. Neurol. Neurosurg. Psychol. 32, 479–483 (1969)
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Bornstein, Y. The pattern evoked responses (VER) in optic neuritis. Albrecht von Graefes Arch. Klin. Ophthalmol. 197, 101–106 (1975). https://doi.org/10.1007/BF00506647
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DOI: https://doi.org/10.1007/BF00506647