Chemistry of heterocycylic N-oxides and related compounds. 12. Diphenylhydroxymethylation of quinoline N-oxide with benzophenone ketyls and dianions
Diphenylhydroxymethylation of the pyridine ring to give diphenyl(2-quinolyl)carfabinol or its N-oxide occurs in the reaction of quinoline N-oxide with benzophenone ketyls and dianions. The best results are obtained when the lithium ketyl is used. A reduction product, viz., quinoline, is formed simultaneously in all of the reactions.
KeywordsLithium Organic Chemistry Pyridine Quinoline Related Compound
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