Chemistry of Heterocyclic Compounds

, Volume 19, Issue 7, pp 796–801 | Cite as

Spectral properties of 8-bromoetheno derivatives of adenine nucleotides

  • T. A. Kondrat'eva
  • R. I. Gvozdev
  • L. V. Tat'yanenko


Imidazo[2,1-i]purine derivatives, viz., etheno-AMP, etheno-ADP, and etheno-ATP, as well as their 8-bromo derivatives, were synthesized by means of α,β-dibromoethyl acetate. The spectral properties of the compounds obtained were studied. It was observed that, with respect to the character of their electronic and fluorescence spectra, the brominated analogs of ethenoadenine nucleotides do not differ from the unbrominated compounds. The introduction of a bromine atom into the imidazo[2,1-i]purine system leads to a decrease (by a factor of 24) in the fluorescence quantum yield and to the appearance of phosphorescence [τ = (2 ± 1)·10−2 sec]. The conformations of the compounds in aqueous solutions were studied.


Acetate Nucleotide Aqueous Solution Organic Chemistry Adenine 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • T. A. Kondrat'eva
    • 1
  • R. I. Gvozdev
    • 1
  • L. V. Tat'yanenko
    • 1
  1. 1.Branch of the Institute of Chemical PhysicsAcademy of Sciences of the USSRChernogolovka

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