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Synthesis and physicochemical properties of thiazolino[3,2-a]benzimidazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 1-β-hydroxyalkyl(aralkyl)-2-chlorobenzimidazoles with thiourea or the reduction of 1-acylmethylbenzimidazoline-2-thiones with sodium borohydride gave 1-β-hydroxyalkyl(aralkyl, hetaryl)benzimidazoline-2-thiones, which were converted to 2-alkyl(aryl, hetaryl)-substituted thiazolino[3,2-a]benzimidazoles by the action of POCl3.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 942–947, July, 1983.

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Krasovskii, A.N., Klyuev, N.A., Roman, A.B. et al. Synthesis and physicochemical properties of thiazolino[3,2-a]benzimidazoles. Chem Heterocycl Compd 19, 756–762 (1983). https://doi.org/10.1007/BF00506103

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  • DOI: https://doi.org/10.1007/BF00506103

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