Zeitschrift für Kinderheilkunde

, Volume 118, Issue 1, pp 63–70 | Cite as

Adrenocortical carcinoma with Ectopic LH production

  • Helmut Gadner
  • Bruno Weber
  • Hansjörg Riehm


This report concerns a 3 1/4-year-old boy, in whom a left-sided adrenocortical adenocarcinoma of predominantly androgenic potency caused isosexual precocious development with enlargement of the testicles and, probably, predominantly testicular testosterone secretion. It was possible to identify an increase in LH production as the cause of this phenomenon; the seat of origin was the tumor. Ectopic LH production was proved upon extraction of the tumor and by the decline of gonadotropic activity after its removal.

Key words

Adrenocortical carcinoma Testosterone Ectopic LH production Precocious androgenization 


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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • Helmut Gadner
    • 1
  • Bruno Weber
    • 1
  • Hansjörg Riehm
    • 1
  1. 1.Kinderklinik der Freien Universität BerlinBerlinGermany

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