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Chemistry of Heterocyclic Compounds

, Volume 21, Issue 1, pp 77–83 | Cite as

Synthesis of 3-cyano-4-aryl-5-ethoxycarbonyl-6-methyl-3,4-dihydropyridine-2-thiones

  • A. A. Krauze
  • É. É. Liepin'sh
  • Yu. É. Pelcher
  • Z. A. Kalme
  • I. V. Dipan
  • G. Ya. Dubur
Article

Abstract

The condensation of ethyl arylidenacetoacetate with cyanothioacetamide and of arylidenecyanothioacetamides with ethyl acetoacetate or of arylidenecyanothioacetamides with ethyl β-aminocrotonate gave 3-cyano-4-aryl-5-ethoxycarbonyl-6-methyl-3,4-dihydropyridine-2-thiones. PMR spectroscopy showed that the 3-cyano-4-aryl-3,4-dihydropyridine-2-thiones are formed as a mixture of cis and trans isomers.

Keywords

Spectroscopy Ethyl Organic Chemistry Trans Isomer Acetoacetate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • A. A. Krauze
    • 1
  • É. É. Liepin'sh
    • 1
  • Yu. É. Pelcher
    • 1
  • Z. A. Kalme
    • 1
  • I. V. Dipan
    • 1
  • G. Ya. Dubur
    • 1
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga

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