Chemistry of Heterocyclic Compounds

, Volume 19, Issue 10, pp 1088–1090 | Cite as

Synthesis and transformations of 1-methyl-4-aryl-7-R-isoquinolines

  • V. S. Shklyaev
  • E. V. Dormidontova
  • R. F. Saraeva
Article
  • 31 Downloads

Abstract

1-Methyl-4-aryl-7-R-isoquinolines were obtained by cyclization of 1,1-diaryl-2-acetamidoethylenes in the presence of phosphorus pentoxide. The condensation of the products with diethyl oxalate leads to the formation of ethyl 1-(4-aryl-7-R-isoquinolyl)pyruvates, which react with o-phenylenediamine to give 1-(4-aryl-7-R-isoquinolyl)-2-[3-(4H)-oxo-2-quinoxalyl]methanes.

Keywords

Methane Phosphorus Ethyl Organic Chemistry Pyruvate 

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • V. S. Shklyaev
    • 1
    • 2
  • E. V. Dormidontova
    • 1
    • 2
  • R. F. Saraeva
    • 1
    • 2
  1. 1.Institute of Continuum Mechanics, Ural Science CenterAcademy of Sciences of the USSRPerm
  2. 2.Perm State Pharmaceutical InstitutePerm

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