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Chemistry of Heterocyclic Compounds

, Volume 17, Issue 5, pp 471–473 | Cite as

Reactions of 2,2-dimethyl-3-phenylazirine with chlorides of unsaturated and amino-substituted acids

  • A. V. Eremeev
  • R. S. Él'kinson
  • V. A. Imuns
Article
  • 28 Downloads

Abstract

The reaction of 2,2-dimethyl-3-phenylazirine with N-phthalylglycine acid chloride gives initially N-acyl-3-chloroaziridine, which undergoes isomerization to a substituted 2-oxazoline and the corresponding keto amide. The reaction of 2,2-di-methyl-3-phenylazirine with the chlorides of crotonic, β- (2-furyl) acrylic, cinnamic, and phenylpropiolic acids in benzene at 20 °C leads to 2,2-dimethylindoxyl and the corresponding unsaturated acid.

Keywords

Chloride Benzene Organic Chemistry Amide Acid Chloride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • A. V. Eremeev
    • 1
  • R. S. Él'kinson
    • 1
  • V. A. Imuns
    • 1
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga

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