Chemistry of Heterocyclic Compounds

, Volume 17, Issue 5, pp 457–458 | Cite as

Synthesis of some 4-thiazolidone derivatives from 4-(cyclo-3-alkenyl)thiosemicarbazones

  • I. V. Smolanka
  • N. P. Man'o
  • T. A. Krasnitskaya
Article

Abstract

The reaction of 4-(cyclo-3-pentenyl)- and 4-(cyclo-3-hexenyl) thiosemicarbazones with chloroacetic acid gave 2-hydrazono derivatives of 3-cyclo-pentenyl (cyclohexenyl) thioazolid-4-one, the condensation of which with aromatic aldehydes gave 5-benzylidene derivatives. Representatives of 4-thiazolidone with a carboxy group in the 5 position were synthesized by condensation of the same thiosemicarbazones with maleic anhydride. Some of the substances obtained have bactericidal activity.

Keywords

Organic Chemistry Aldehyde Bactericidal Activity Anhydride Carboxy 

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Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • I. V. Smolanka
    • 1
  • N. P. Man'o
    • 1
  • T. A. Krasnitskaya
    • 1
  1. 1.Uzhgorod State UniversityUzhgorod

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