Chemistry of Heterocyclic Compounds

, Volume 17, Issue 5, pp 457–458 | Cite as

Synthesis of some 4-thiazolidone derivatives from 4-(cyclo-3-alkenyl)thiosemicarbazones

  • I. V. Smolanka
  • N. P. Man'o
  • T. A. Krasnitskaya


The reaction of 4-(cyclo-3-pentenyl)- and 4-(cyclo-3-hexenyl) thiosemicarbazones with chloroacetic acid gave 2-hydrazono derivatives of 3-cyclo-pentenyl (cyclohexenyl) thioazolid-4-one, the condensation of which with aromatic aldehydes gave 5-benzylidene derivatives. Representatives of 4-thiazolidone with a carboxy group in the 5 position were synthesized by condensation of the same thiosemicarbazones with maleic anhydride. Some of the substances obtained have bactericidal activity.


Organic Chemistry Aldehyde Bactericidal Activity Anhydride Carboxy 
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Literature cited

  1. 1.
    F. J. Wilson and R. J. Burus, J. Chem. Soc., 121, 870 (1922).Google Scholar
  2. 2.
    E. V. Vladzimirskaya, Zh. Obshch. Khim., 28, 1505 (1958).Google Scholar
  3. 3.
    O. F. Pavlenko, Farm. Zh., 4, 3 (1959).Google Scholar
  4. 4.
    N. M. Turkevich and E. V. Vladzimirskaya, Zh. Obshch. Khim., 24, 2010 (1954).Google Scholar
  5. 5.
    N. O. Saldabol and A. Ya. Medne, Izv. Akad. Nauk Latv. SSR, Ser. Khim., 465 (1964).Google Scholar
  6. 6.
    V. S. Misra and A. Saxena, J. Prakt. Chem., 36, 260 (1967).Google Scholar
  7. 7.
    Ya. S. Frankevich, Farm. Zh., 3, 11 (1967).Google Scholar
  8. 8.
    I. V. Smolanka and N. P. Man'o, Ukr. Khim. Zh., 35, 508 (1969).Google Scholar

Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • I. V. Smolanka
    • 1
  • N. P. Man'o
    • 1
  • T. A. Krasnitskaya
    • 1
  1. 1.Uzhgorod State UniversityUzhgorod

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