Summary
The reflex amplitude of GS α-motoneurons monosynaptically excited by Ia spindle afferents in cats with intercollicular decerebration was remarkably decreased in a parallel shift downwards from control by 10 mg/kg i.v. DMAA.
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References
Matthews, P. B. C.: Mammalian muscle receptors and their central actions. London: Edw. Arnold Ltd. 1972
Schwab, R. S., England, A. C., Jr., Poskanzer, D. C., Young, R. Y.: Amantadine in the treatment of Parkinson's disease. J. Amer. med. Ass. 208, 1168–1170 (1969)
Sontag, K.-H., Wand, P.: Decrease of muscle rigidity by dimethylaminoadamantan (DMAA) in intercollicularly decerebrated cats. Arzneimittel-Forsch. (in press) (1973)
Svensson, T. H.: Dopamine release and direct dopamine receptor activation in the central nervous system by dimethylaminoadamantan, an amantadine derivative. Europ. J. Pharmacol. 23, 232–238 (1973)
Thoden, U., Margherini, P. C., Pompeiano, O.: Evidence that presynaptic inhibition may decrease the autogenetic excitation caused by vibration of extensor muscles. Arch. ital. Biol. 110, 90–116 (1972)
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Mühlberg, B., Sontag, KH. The depression of monosynaptically excited α-motoneurons during vibration reflex by dimethylaminoadamantan (DMAA). Naunyn-Schmiedeberg's Arch. Pharmacol. 280, 113–116 (1973). https://doi.org/10.1007/BF00505361
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DOI: https://doi.org/10.1007/BF00505361