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Archives of oto-rhino-laryngology

, Volume 232, Issue 2, pp 107–115 | Cite as

Oncocytic lesions of the larynx

  • A. Ferlito
  • G. Recher
Article

Summary

Three cases of oncocytic lesions of the larynx diagnosed at the Section of Pathology, Dep. of Otolaryngology, Padua University from November 1974 until December 1980 are reported. The lesion is uncommon but not exceptional and occurs in elderly people. Problems connected with pathology and the clinico-therapeutic approach are dealt with. The pathogenesis of the lesion is also discussed, with particular stress on whether it is a true neoplasm or a process of metaplasia-hyperplasia from the ductal epithelium in connection with senile involution of the upper respiratory tract.

Key words

Cysts of the larynx Laryngeal pathology Non-neoplastic diseases of the larynx 

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References

  1. Arcidiacono G, Lomeo G (1958) II cistoadenoma papillifero delle ghiandole salivari. Osservazione di due casi a localizzazione nel vestibolo laringeo. Clinica ORL 10:1–14Google Scholar
  2. Allegra SR (1971) Warthin's tumor: a hypersensitivity disease? Ultrastuctural, light, and immunofluorescent study. Hum Pathol 2:403–420Google Scholar
  3. Andrew W (1949) Quoted by Busuttil A (1976)Google Scholar
  4. Balogh K, Roth SI (1965) Histochemical and electron microscopic studies of eosinophilic granular cells (oncocytes) in tumors of the parotid gland. Lab Invest 14: 310–320Google Scholar
  5. Barbaccia F, Nicelli F, Tosi C (1956) Adenolinfoma della laringe. Arch Ital Otol Rinol Laringol 67:887–896Google Scholar
  6. Barton RT (1972) Oxyphilic adenoma of the larynx. Ann Otol Rhinol Laryngol 81:256–257Google Scholar
  7. Bell RD, Chamberlain D, Jahn AF (1978) Oncocytic lesions of the larynx. J Otolaryngol 7:211–217Google Scholar
  8. Brandenburg JH (1967) Oncocytic cyst of the larynx. Ann Otol Rhinol Laryngol 76:220–223Google Scholar
  9. Busuttil A (1976) Oncocytic lesions of the upper respiratory tract. J Laryngol Otol 90:277–288Google Scholar
  10. Capo OA (1965) Oxyphilic adenoma (oncocytoma) of the larynx. Presentation of a case. Arch Otolaryngol 82:42–44Google Scholar
  11. De Santo LW, Devine KD, Weiland LH (1970) Cysts of the larynx. Classification. Laryngoscope 80: 145–176Google Scholar
  12. Donald PJ, Krause CJ (1973) Papillary cystadenoma of the larynx. Laryngoscope 83:2024–2028Google Scholar
  13. Drut R, Di Rago CA, Di Rago CA (1975) Cistoadenoma papilar linfomatoso (tumor de Warthin) de laringe. An Otorrinolaringol Ibero Am 3:207–211Google Scholar
  14. Ekedahl C, Schnürer LB (1969) Eosinophilic papillary cystadenoma of the larynx. Acta Otolaryngol 67:467–470Google Scholar
  15. Figi FA, Rowland WD, New GB (1944) Cystadenoma of the larynx. Report of four cases. Arch Otolaryngol 40:445–450Google Scholar
  16. Gallagher JC, Puzon BQ (1969) Oncocytic lesions of the larynx. Ann Otol Rhinol Laryngol 78:307–318Google Scholar
  17. Hamperl H (1950) Onkocytes and the so-called Hürthle cell tumor. Arch Pathol 49: 563–567Google Scholar
  18. Heath D (1961) Eosinophilic granular-cell cystadenoma of the larynx. J Laryngol Otol 75:679–684Google Scholar
  19. Holm-Jensen S, Jacobsen M, Thommesen N, Ferreira O (1977) Oncocytic cysts of the larynx. Acta Otolaryngol 83:366–371Google Scholar
  20. Howarth W, Chamings AJ (1934) Cystic adenomata of the ventricles of Morgagni. J Laryngol Otol 49:324–325Google Scholar
  21. Kleinsasser O, Klein HJ, Steinbach E, Hübner G (1966) Onkocytäre adenomartige Hyperplasien, Adenolymphome und Onkocytome der Speicheldrüsen. Arch Klin Exp Ohren-Nasen-Kehlkopfheilkd 186:317–336Google Scholar
  22. Kroe DJ, Pitcock JA, Cocke EW (1967) Oncocytic papillary cystadenoma of the larynx. Presentation of two cases. Arch Pathol 84:429–432Google Scholar
  23. Kuhn AJ (1961) Cystadenoma of the parotid gland and larynx. Arch Otolaryngol 73: 404–406Google Scholar
  24. Le Jeune FE, Putman HC, Yamase HT (1980) Multiple oncocytic papillary cystadenomas of the larynx: a case report. Laryngoscope 90:501–504Google Scholar
  25. Lennox B (1948) Quoted by Busuttil A (1976)Google Scholar
  26. Mendonca DR, Ward AM (1973) Oxyphil adenoma of the laryngeal ventricle. J Laryngol Otol 87:583–585Google Scholar
  27. Møller J, Ørntoft I (1965) Laryngeal oncocytoma. Acta Otolaryngol 60:239–242Google Scholar
  28. Mollica V, Rossi G (1951) Il problema degli oncociti e il loro significato nella mucosa laringea in condizioni normali. Riv Anat Patol Oncol 4:1179–1200Google Scholar
  29. Mollica V, Rossi G (1952) Gli oncociti nelle varie affezioni patologiche della laringe. Riv Anat Patol Oncol 5:231–244Google Scholar
  30. Nassar VH, Bridger GP (1971) Topography of the laryngeal mucous glands. Arch Otolaryngol 94:490–498Google Scholar
  31. Nohteri H (1946) A case of laryngeal cyst composed of oncocytes and the appearance of oncocytes in the mucous membrane of the nose and the larynx. Acta Pathol Microbiol Scand 23:473–483Google Scholar
  32. Noyek AM, Pritzker KPH, Greyson ND, Blackstein M, Chapnik JS, Shapiro BJ (1980) Familial Warthin's tumor. 1. Its synchronous occurrence in mother and son. 2. Its association with cystic oncocytic metaplasia of the larynx. J Otolaryngol 9:90–96Google Scholar
  33. Oliveira CA, Roth JA, Adams GL (1977) Oncocytic lesions of the larynx. Laryngoscope 87: 1718–1725Google Scholar
  34. Pinkerton PH, Swanson Beck J (1961) Eosinophilic granular-cell (oncocytic) cysts of the larynx. J Pathol Bacteriol 81:532–534Google Scholar
  35. Ranger D, Thackray AC (1953) Papillary cystadenoma of the larynx. J Laryngol Otol 67:609–614Google Scholar
  36. Redaelli GA, D'Ascanio GF, Ferrarini A (1979) Adenoma ossifilo del ventricolo laringeo. Valsalva 55:58–61Google Scholar
  37. Som ML, Peimer R (1949) Oncocytic cystadenoma of the larynx. Ann Otol Rhinol Laryngol 58:234–242Google Scholar
  38. Steglich-Petersen J (1966) Eosinophilic papillary cystadenoma of the larynx. Acta Otolaryngol 62:505–512Google Scholar
  39. Stewart EF (1960) Cystadenoma of larynx. J Laryngol Otol 74: 325–330Google Scholar
  40. Tiwari RM, Williams HI (1969) Adenolymphoma in a laryngocoele. J Laryngol Otol 83:1227–1230Google Scholar
  41. Yamase HT, Putman HC (1979) Oncocytic papillary cystadenomatosis of the larynx. A clinicopathologic entity. Cancer 44:2306–2311Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • A. Ferlito
    • 1
  • G. Recher
    • 1
  1. 1.Dept. of OtolaryngologyUniversity of PaduaPaduaItaly

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