Summary
The release of acetylcholine evoked by field stimulation of the guinea-pig ileum (3 Hz) is increased by yohimbine and tolazoline but not affected by phentolamine. It is proposed that yohimbine and tolazoline by blocking α-adrenoceptors of the cholinergic nerves abolish the inhibition caused by endogenous noradrenaline, and thus facilitate the output of acetylcholine.
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Kilbinger, H., Wessler, I. Increase by α-adrenolytic drugs of acetylcholine release evoked by field stimulation of the guinea-pig ileum. Naunyn-Schmiedeberg's Arch. Pharmacol. 309, 255–257 (1979). https://doi.org/10.1007/BF00504758
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DOI: https://doi.org/10.1007/BF00504758