Abstract
Isothiazolium salts, which are readily hydrolyzed to heterocyclic o-formyl disulfides, were obtained by alkylating bicyclic systems containing an isothiazole ring. The initial isothiazole-containing systems are stable in water and react with nucleophiles such as the hydroxyl ion with opening of the isothiazole ring and formation of o-cyanodisulfides.
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L. V. Alam, I. Ya. Kvitko, and A. V. El'tsov, Zh. Org. Khim., 13, 863 (1977).
I. Ya. Kvitko and B. A. Porai-Koshits, Zh. Org. Khim., 5, 1685 (1969).
T. W. Thompson, J. Chem. Soc., Chem. Commun., 532 (1968).
S. Gronowitz and N. Gjs, Acta Chem. Scand., 21, 2838 (1967).
D. S. Ayres and J. R. Smith, J. Chem. Soc., C, 2737 (1968).
H. A. Staab and A. Mannschreck, Ber., 98, 1111 (1965).
S. P. Fradkina, N. S. Fedorova, and I. Ya. Kvitko, Zh. Org. Khim., 21, 203 (1985).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 223–226, February, 1985.
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Alam, L.V., Kvitko, I.Y. & Fedorova, N.S. Transformations of bicyclic systems containing an isothiazole ring. Chem Heterocycl Compd 21, 185–188 (1985). https://doi.org/10.1007/BF00504206
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DOI: https://doi.org/10.1007/BF00504206