Synthesis of pyridine and quinoline derivatives of ferrocene from β-chloro-β-ferrocenylacrolein
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2-Ferrocenylquinolines that contain a hydroxy or methoxy group in the 7 position were obtained by the reaction of β-chloro-β-ferrocenylacrolein with m-anisidine and with m-aminophenol. The introduction of aniline in this reaction leads to the formation of β-ferrocenyl-β-phenylaminoacrolein anil hydrochloride, which cannot be converted to 2-ferrocenylquinoline. 2,3,6-Trisubstituted pyridines that contain a ferrocenyl substituent in the 6 position were obtained by condensation of β-chloro-β-ferrocenylacrolein with β-dicarbonyl compounds.
KeywordsOrganic Chemistry Pyridine Hydrochloride Aniline Methoxy
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