Summary
Electron microscopy of negatively stained plasma shows that intravenous administration of heparin to healthy humans results in a fast degradation of very low density lipoproteins (VLDL), which are very rich in triglycerides (50% w/w). VLDL are also rapidly digested by post-heparin lipolytic activity when serum from non-heparinized subjects is incubated at 27°C “in vitro” with post-heparin serum of healthy controls.
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Abbreviations
- VLDL:
-
very low density lipoproteins
- LDL:
-
low density lipoproteins
- HDL:
-
high density lipoproteins
- LP-X:
-
lipoprotein-X, abnormal lipoprotein characterizing obstructive jaundice
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Agostini, B. The effect of post-heparin lipolytic activity on plasma lipoproteins. Histochemistry 40, 215–220 (1974). https://doi.org/10.1007/BF00501956
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DOI: https://doi.org/10.1007/BF00501956