Skip to main content
Log in

Studies on the sympathetic nervous system in tetanus

  • Original Papers
  • Published:
Naunyn-Schmiedeberg's Archives of Pharmacology Aims and scope Submit manuscript

Summary

Cardiovascular and other abnormalities are described in ten patients with severe tetanus, with particular emphasis on cardiac output and related variables. The disturbances are attributed to pathological overactivity of the sympathetic nervous system.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Ablett, J. J. L.: An analysis and main experiences in 82 patients treated in the Leeds Tetanus Unit. Symposium on tetanus in Great Britain held at Leeds on 7–8 April, 1967, pp. 1–10. United Leeds Hospital. M. Ellis, ed. (1967).

  • Bevegard, B. S., Shepherd, J. T.: Regulation of the circulation during exercise in man. Physiol. Rev. 47, 178–213 (1967).

    Google Scholar 

  • Brooke, J. D., Hamley, E. J., Thomason, H.: Relationship of heart rate to physical work. J. Physiol. (Lond.) 197, 61–63P (1968).

    Google Scholar 

  • Clark, M. M., Taylor, J. F. N.: Some problems encountered in a severe case of tetanus. Brit. J. Anaesth. 38, 840–842 (1966).

    Google Scholar 

  • Corbett, J. L., Kerr, J. H., Prys-Roberts, C., Crampton Smith, A., Spalding, J. M. K.: Cardiovascular disturbances in severe tetanus due to overactivity of the sympathetic nervous system. Anaesthesia 24, 198–212 (1969).

    Google Scholar 

  • Cotes, J. E.: Lung Function: Assessment and Application in Medicine, 2nd ed. Blackwell: Oxford and Edinburgh 1968.

    Google Scholar 

  • Dean, H. R.: A report on 25 cases of tetanus. Lancet I, 673–680, 1917.

    Google Scholar 

  • Furnival, C. M., Linden, R. J., Snow, H. M.: Response to stimulation of the cardiac sympathetic nerves. J. Physiol. (Lond.) 197, 74–75P (1968).

    Google Scholar 

  • Garcia-Palmieri, M. R., Ramirez, R.: Generalized tetanus: analysis of 202 cases. Ann. intern. Med. 47, 721–730 (1957).

    Google Scholar 

  • Glossop, M. W., Low, M. D. W.: Some observations on severe tetanus. Treatment by paralysis and intermittent positive pressure ventilation. Brit. J. Anaesth. 29, 326–331 (1957).

    Google Scholar 

  • Hanson, J. S., Tabakin, B. S., Levy, A. M.: Comparative exercise-cardiorespiratory performance of normal men in the third, fourth and fifth decades of life. Circulation 37, 345–360 (1968).

    Google Scholar 

  • Hobday, J. D., Baker, A. J.: Guillain-Barré syndrome complicated by hypertension and ileitis. Med. J. Aust. 2, 536–538 (1968).

    Google Scholar 

  • Jones, N. L.: Exercise testing. Brit. J. Dis. Chest 61, 169–189 (1967).

    Google Scholar 

  • Kelman, G. R.: Digital computer subroutine for the conversion of oxygen tension into saturation. J. appl. Physiol. 21, 1375–1376 (1966).

    Google Scholar 

  • Kloetzel, K.: Clinical patterns in severe tetanus. J.Amer. med. Ass. 185, 559–567 (1963).

    Google Scholar 

  • Lloyd, B. B.: A development of Haldane's gas analysis apparatus. J. Physiol. (Lond.) 143, 5P (1958).

    Google Scholar 

  • Marshall, R. J., Shepherd, J. T.: Cardiac Function in Health and Disease. Philadelphia-London-Toronto: Saunders 1968.

    Google Scholar 

  • McHardy, G. J. R., Shirling, D., Passmore, R.: Basic Techniques in Human Metabolism and Respiration. Blackwell: Oxford 1967.

    Google Scholar 

  • Montgomery, R. D.: The cause of death in tetanus. W. Indian med. J. 10, 84–102 (1961).

    Google Scholar 

  • Ostfeld, A. M.: Sustained hypertension after poliomyelitis. Arch. intern. Med. 107, 551–557 (1961).

    Google Scholar 

  • Perlstein, M. A., Andelman, M. B., Rosner, D. C., Wehrle, P.: Incidence of hypertension in poliomyelitis. Paediatrics 11, 628–633 (1953).

    Google Scholar 

  • Richards, D. W.: Circulatory effects of hyperventilation and hypoventilation. In: Handbook of Physiology, section 2, vol. 3, pp. 1887–1897. Washington: American Physiological Society 1965.

    Google Scholar 

  • Sarnoff, S. J., Mitchell, J. H.: Control of the function of the heart. In: Handbook of Physiology, section 2: Circulation, 1, pp. 489–532, Washington: American Physiological Society 1962.

    Google Scholar 

  • Spencer, W. A., Jackson, R. R., Vallbona, C., Harrison, G. M.: Circulatory disturbances in life-threatening poliomyelitis. Amer. Heart J. 59, 384–400 (1960).

    Google Scholar 

  • Stirnemann, H.: Tetanus. Bern-Stuttgart: Hans Huber 1966.

    Google Scholar 

  • Tenney, S. M., Lamb, T. W.: Physiological consequences of hyperventilation and hypoventilation. Handbook of Physiology, section 3: Respiration, vol. 2, pp. 979–1010. Washington: American Physiological Society 1965.

    Google Scholar 

  • Tyler, H. R., Dawson, D.: Hypertension and its relation to the nervous system. Ann. intern. Med. 55, 681–694 (1961).

    Google Scholar 

  • Zimanyi, L., Prohaszka, M., Szondy, M., Orami, S.: Arterial hypertension after poliomyelitis. Acta med. scand. 164, 497–505 (1959).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Corbett, J.L., Harris, P.J. Studies on the sympathetic nervous system in tetanus. Naunyn-Schmiedeberg's Arch. Pharmacol. 276, 447–460 (1973). https://doi.org/10.1007/BF00499897

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00499897

Key words

Navigation