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The protective effect of hydantoin treatment on carcinogenesis

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Summary

Hydantoin reduced the incidence of urethane induced lung adenomas in SWR mice. This tumor protective effect might be attributed to the modifying effect of the drug on the immunological system of the treated mice.

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References

  • Burnet, F. M.: Immunological factors in the process of carcinogenesis. Brit. med. Bull. 20, 154 (1964)

    Google Scholar 

  • Easton, J. D.: Potential hazards of hydantoin use. Ann. intern. Med., 77, 998 (1972)

    Google Scholar 

  • Grob, P. J., Herold, G. E.: Immunological abnormalities and hydantoins. Brit. med. J. 1972 II 561

  • Sorrell, T. C., Forbes, I. J., Burness, F. R., Rischbieth, R. H. C.: Depression of immunological function in patients treated with phenytoin sodium (sodium diphenylhydantoin). Lancet 1971 II, 1233

  • Trainin, N., Linker-Israeli, M., Small, M., Boiato-Chen, L.: Enhancement of lung adenoma formation by neonatal thymectomy in mice treated with 7,12-Dimethylbenz (a) anthracene or urethane. Int. J. Cancer 2, 326 (1967)

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Levo, Y. The protective effect of hydantoin treatment on carcinogenesis. Naunyn-Schmiedeberg's Arch. Pharmacol. 285, 29–30 (1974). https://doi.org/10.1007/BF00499526

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  • DOI: https://doi.org/10.1007/BF00499526

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