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Condensed imidazo-1,2,4-azines 22. Alkylation of 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Substituted 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones react with alkyl (alkenyl) halides, 2-chloroethanol, glycerin dichlorohydrin, haloacetic acids, the methyl ester and amide of monochloroacetic acid in a methanol-sodium methylate system to form N(5)-alkylation products, and with hydroxylamino-O-sulfonic acid to form 5-aminoimidazo[1,2-b]-1,2,4-triazepin-4-one.

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For Communication 21, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 234–236, February, 1990.

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Kruglenko, V.P., Idzikovskii, V.A., Kobets, N.N. et al. Condensed imidazo-1,2,4-azines 22. Alkylation of 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones. Chem Heterocycl Compd 26, 201–203 (1990). https://doi.org/10.1007/BF00499416

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  • DOI: https://doi.org/10.1007/BF00499416

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