Biochemical Genetics

, Volume 24, Issue 9–10, pp 721–727 | Cite as

Linkage of Pep-2 and Apk on mouse chromosome 10

  • James E. Womack
  • Shawn Ashley
  • Lois B. Barnett
  • Susan E. Lewis
Article

Abstract

An ethylnitrosourea (ENU)-induced electrophoretic variant of mouse PEP-2, a tripeptidase, has been used to determine the location of the structural gene on chromosome 10. Gene order and recombination frequencies were estimated as Apk-21.8±3.9%-Pep-2-3.7±2.1%-Sl. Methods for rapid determination of Apk and Pep-2 alleles by cellulose acetate electorphoresis and a valuable linkage testing stock carrying the unique Apkm and Pep-2b alleles are described.

Key words

mouse peptidase-2 acid phosphatase linkage chromosome 10 

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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • James E. Womack
    • 1
  • Shawn Ashley
    • 1
  • Lois B. Barnett
    • 2
  • Susan E. Lewis
    • 2
  1. 1.Department of Veterinary PathologyTexas A&M UniversityCollege Station
  2. 2.Chemistry and Life Sciences GroupResearch Triangle InstituteResearch Triangle Park

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