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Stereochemistry of the oxidation and alkylation of trans-1-alkyl-4-ethynyldecahydro-4-quinolols

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The stereochemistry of the oxidation and alkylation of the nitrogen atom of trans-1-alkyl-4-ethynyldecahydro-4-quinolols was investigated. The orientation of the substitutents attached to the nitrogen atom in the synthesized N-oxides and quaternary salts was determined on the basis of the PMR spectra and previously obtained data on the stereochemistry of the oxidation of 4-substituted 1,3-dimethyldecahydro-4-quinolols.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry, Academy of Sciences of the Belorussian SSR, 220600, Minsk

    A. A. Akhrem, L. I. Ukhova, N. F. Marchenko, G. P. Kukso & V. M. Gorul'ko

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  1. A. A. Akhrem
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  2. L. I. Ukhova
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  3. N. F. Marchenko
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  4. G. P. Kukso
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  5. V. M. Gorul'ko
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 221–224, February, 1977.

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Akhrem, A.A., Ukhova, L.I., Marchenko, N.F. et al. Stereochemistry of the oxidation and alkylation of trans-1-alkyl-4-ethynyldecahydro-4-quinolols. Chem Heterocycl Compd 13, 177–180 (1977). https://doi.org/10.1007/BF00497873

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  • DOI: https://doi.org/10.1007/BF00497873

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