Skip to main content
SpringerLink
Log in

Primary hyperparathyroidism in children

  • Case Report
  • Published:
Pediatric Surgery International Aims and scope Submit manuscript

Abstract

Primary hyperparathyroidism is an uncommon condition in childhood that is easily amenable to surgical treatment with excellent results. Pathologically, the parathyroid glands may show generalized hyperplasia or, more commonly, adenoma formation, the latter frequently being seen in adolescence. Two girls with solitary parathyroid adenomas and predominantly skeletal manifestations resembling rickets are reported, underlining the need to suspect and appropriately investigate these children. The literature on the subject is reviewed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bergenfelz A, Tennvall J, Ahren B (1992) Thallium-technetium subtraction scintigraphy of enlarged parathyroid glands after calcitonin stimulation of parathyroid hormone secretion. Acta Radiol 33: 319–322

    PubMed  CAS  Google Scholar 

  2. Bjernulf A, Hall K, Sgogren I et al (1970) Primary hyperparathyroidism in children. Acta Pediatr Scand 59: 249–258

    Article  CAS  Google Scholar 

  3. Block WC III, Utley JR (1968) The differential diagnosis of parathyroid adenoma and chief cell hyperplasia. Am J Clin Pathol 49: 761–775

    Google Scholar 

  4. Boey JH, Cooke TJC, Gilber JM, Sweeney EC, Taylor S (1975) Occurrence of other endocrine tumours in primary hyperparathyroidism. Lancet II: 781–784

    Article  Google Scholar 

  5. Davies DR, Dent CE, Watsin L (1968) Tertiary hyperparathyroidism. Br Med J 3: 395–399

    Article  PubMed  CAS  Google Scholar 

  6. Fialkow PJ, Jackson CE, Block MA, et al (1977) Multicellular origin of parathyroid “adenoma”. N Engl J Med 29: 696–697

    Article  Google Scholar 

  7. Girard RM, Belanger A, Hazel B (1982) Primary hyperparathyroidism in children. Can J Surg 25: 11–13, 32

    PubMed  CAS  Google Scholar 

  8. Heath H, Hodgson SF, Kennedy MA (1980) Primary hyperparathyroidism. Incidence, morbidity and potential economic impact in a community. N Engl J Med 302: 189–193

    Article  PubMed  Google Scholar 

  9. Malek RS, Panayotis PK (1976) Urologic manifestations of hyperparathyroidism in childhood. J Urol 15: 717–719

    Google Scholar 

  10. Mannix HJ (1975) Primary hyperparathyroidism in children. Am J Surg 129: 528–531

    Article  PubMed  Google Scholar 

  11. Maria A, Thompson NW (1982) Familial hyperparathyroidism caused by solitary adenomas. Surgery 92: 486–490

    Google Scholar 

  12. Menon PSN, Madhavi N, Mukhopadhyaya S, Padhy AK, Bal CS, Sharma LK (1994) Primary hyperparathyroidism in a 14 year old girl presenting with bone deformities. J Pediatr Child Health 30: 441–443

    Article  CAS  Google Scholar 

  13. Nishiyama RH, Farhi D, Thompson NW (1979) Radiation exposure and the simultaneous occurrence of primary hyperparathyroidism and thyroid nodules. Surg Clin North Am 59: 65–75

    PubMed  CAS  Google Scholar 

  14. Nolan RB, Hayles AB, Woolner LB (1960) Adenoma of the parathyroid gland in children. Report of case and brief review of the literature. Am J Dis Child 99: 622–627

    CAS  Google Scholar 

  15. Rapaport D, Ziv Y, Rubin M, Huminer D, Dinstman M (1986) Primary hyperparathyroidism in children. J Pediatr Surg 21: 395–397

    Article  PubMed  CAS  Google Scholar 

  16. Rudberg C, Akerstrom G, Palmer M et al (1986) Later results of operation for primary hyperparathyroidism in 441 patients. Surgery 99: 643–651

    PubMed  CAS  Google Scholar 

  17. Shelling DH (1935) The parathyroids in health and disease. Kimpton, London, p 100

    Google Scholar 

  18. Sommer B, Welter HF, Spelsberg F, Scherer U, Lissner J (1982) Computed tomography for localizing enlarged parathyroid glands in primary hyperparathyroidism. J Comput Assist Tomogr 6: 521–526

    Article  PubMed  CAS  Google Scholar 

  19. Spritzer CE, Gefter WB, Hamilton R, et al (1987) Abnormal parathyroid glands. High resolution MR imaging. Radiology 162: 487–491

    PubMed  CAS  Google Scholar 

  20. Stark DD, Gooding GAW, Moss AA, Clark OH, Ovenfors C-O (1983) Parathyroid imaging: comparison of high-resolution CT and high-resolution sonography. Am J Roentgenol 141: 633–638

    Article  CAS  Google Scholar 

  21. Thompson NW (1986) Thyroid and parathyroid. In: Welch KJ, Randolph JG, Ravitch MM, O'Neill JA Jr, Rowe MI (eds) Pediatric surgery. Year Book Medical Publishers, Chicago, pp 522–533

    Google Scholar 

  22. Thompson NW, Carpenter LC, Kessler DL, Nishiyama RH (1978) Hereditary neonatal hyperparathyroidism. Arch Surg 113: 100–103

    Article  PubMed  CAS  Google Scholar 

  23. Van Heerden JA, James EM, Kasell PR, Charboneau JW, Grant CS, Purnell DC (1982) Small part ultrasonography in primary hyperparathyroidism. Ann Surg 195: 774–780

    Article  PubMed  Google Scholar 

  24. Winter RJ (1990) Hyperparathyroidism. In: Raffensperger JG (ed) Swenson's pediatric surgery. Appleton and Lange, Connecticut, pp 933–936

    Google Scholar 

  25. Young AE, Gaunt JI, Croft DN, Collins RE, Wells CP, Coakley AJ (1983) Location of parathyroid adenomas by thallium-201 and technetium-99m subtraction scanning. Br Med J 286: 1384–1386

    Article  CAS  Google Scholar 

  26. Young TO, Saltzstein EC, Boman DA (1984) Parathyroid carcinoma in a child: unusual presentation with seizures. J Pediatr Surg 19: 194–196

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatric Surgery, All India Institute of Medical Sciences, 110029, New Delhi, India

    R. Kataria, S. Agarwala & D. K. Mitra

  2. Department of Pediatrics, All India Institute of Medical Sciences, 110029, New Delhi, India

    G. Kaur & P. S. N. Menon

  3. Department of Surgical Disciplines, All India Institute of Medical Sciences, 110029, New Delhi, India

    T. K. Chattopadhyay

  4. Department of Nuclear Medicine, All India Institute of Medical Sciences, 110029, New Delhi, India

    C. S. Bal

Authors
  1. R. Kataria
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Agarwala
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. K. Mitra
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Kaur
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. T. K. Chattopadhyay
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. C. S. Bal
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. P. S. N. Menon
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kataria, R., Agarwala, S., Mitra, D.K. et al. Primary hyperparathyroidism in children. Pediatr Surg Int 11, 374–377 (1996). https://doi.org/10.1007/BF00497816

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00497816

Key words

Search

Navigation