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Indole derivatives

CVII. General method for the preparation of α-(3-indolyl) aliphatic acids

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A method for the preparation of α-(3-indolyl) aliphatic acids, including those containing functional groups (COOH, C≡N), which is based on alkylation of N-carbomethoxy-3-indolylcyanoacetic ester, was developed.

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Literature cited

  1. O. D. Shalygina, L. Kb. Vinograd, and N. N. Suvorov, Khim. Geterotsikl. Soedin., 795 (1975).

  2. R. Barlow, Introduction to Chemical Pharmacology [Russian translation], Moscow (1959), p. 231.

  3. J. Dockx, Syntheses, (1973), p. 441.

  4. V. S. Rozhkov, Yu. I. Smushkevich, T. A. Kozik, and N. N. Suvorov, Khim. Geterotsikl. Soedin., 1502 (1974).

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Authors and Affiliations

  1. D. I. Mendeleev Chemical-Engineering Institute, Moscow

    V. S. Rozhkov, Yu. I. Smushkevich & N. N. Suvorov

Authors
  1. V. S. Rozhkov
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  2. Yu. I. Smushkevich
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  3. N. N. Suvorov
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Additional information

See [1] for communication CVI.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 942–945, July, 1975.

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Rozhkov, V.S., Smushkevich, Y.I. & Suvorov, N.N. Indole derivatives. Chem Heterocycl Compd 11, 826–828 (1975). https://doi.org/10.1007/BF00497305

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  • DOI: https://doi.org/10.1007/BF00497305

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