European Journal of Pediatrics

, Volume 141, Issue 2, pp 81–88 | Cite as

Turner syndrome: Spontaneous growth in 150 cases and review of the literature

  • M. B. Ranke
  • H. Pflüger
  • W. Rosendahl
  • P. Stubbe
  • H. Enders
  • J. R. Bierich
  • F. Majewski
Original Investigations


The spontaneous growth of 150 patients with Turner syndrome from three German centers-90 with 45,X0 constitution, 60 with other chromosomal abnormalities-has been analyzed. The mean adult height was found to be (n=14) 146.8 cm. It was observed that growth in these patients can be divided into four phases: (1) Intrauterine growth, which is retarded; (2) Height development, which is normal up to abone-age of about 2 years; (3) Between a bone-age of 2 and 11 years when stunting of growth is most marked; (4) After a bone-age of 11 years—the time at which puberty should normally start—the growth phase is prolonged, but total height gain is only little below normal levels. No difference in height could be observed between cases with X0 karyotype and other chromosomal variants. The data are compared with those in the literature.

Key words

Turner syndrome Growth 


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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • M. B. Ranke
    • 1
  • H. Pflüger
    • 1
  • W. Rosendahl
    • 1
  • P. Stubbe
    • 2
  • H. Enders
    • 3
  • J. R. Bierich
    • 1
  • F. Majewski
    • 4
  1. 1.Children's HospitalUniversity of TübingenFederal Republic of Germany
  2. 2.Children's HospitalUniversity of GöttingenFederal Republic of Germany
  3. 3.Institute for Anthropology and Human GeneticsUniversity of TübingenFederal Republic of Germany
  4. 4.Institute for Anthropology and Human GeneticsUniversity of DüsseldorfFederal Republic of Germany

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