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Enhancement by chlordiazepoxide of the anticholinergic-induced locomotor stimulation in mice

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Abstract

Spontaneous locomotor activity has been studied in mice treated with chlordiazepoxide, atropine, and scopolamine, given alone or in combination. Chlordiazepoxide alone increased activity for a short time, while the two anticholinergic drugs produced longer lasting stimulatory effects. Locomotor stimulation was stronger when chlordiazepoxide and anticholinergics were given in combination.

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Authors and Affiliations

  1. Institute of Pharmacology, P.A.N., Krakow, Poland

    Jozef Hano

  2. Laboratorio di Psicobiologia e Psicofarmacologia, C.N.R., via Reno n. 1, 00198, Roma, Italy

    Mario Sansone

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  1. Mario Sansone
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  2. Jozef Hano
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Sansone, M., Hano, J. Enhancement by chlordiazepoxide of the anticholinergic-induced locomotor stimulation in mice. Psychopharmacology 64, 181–184 (1979). https://doi.org/10.1007/BF00496059

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  • DOI: https://doi.org/10.1007/BF00496059

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