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ACTH-like immunoreactivity in the gastrin cell. Independent changes in gastrin and ACTH-like immunoreactivity during ontogeny

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Summary

Rat antral gastrin cells have been shown to contain ACTH-like immunoreactivity. Studies on the ontogeny of the antral gastrin cells reveal that these cells start to store gastrin before they contain detectable quantities of ACTH-like immunoreactivity. At no stage studied were duodenal gastrin cells found to contain ACTH-like peptides. The data indicate that the G cells synthetizes and/or releases the two hormonal peptides independently.

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  1. Institute of Medical Biochemistry, University of Aarhus, DK-8000, Aarhus C, Denmark

    L.-I. Larsson

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  1. L.-I. Larsson
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Larsson, LI. ACTH-like immunoreactivity in the gastrin cell. Independent changes in gastrin and ACTH-like immunoreactivity during ontogeny. Histochemistry 56, 245–251 (1978). https://doi.org/10.1007/BF00495986

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  • DOI: https://doi.org/10.1007/BF00495986

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