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The effects of acetylcholine on bulbar respiratory related neurones

Consequences of anaesthesia by pentobarbital

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Summary

The effects of cholinergic agonists and antagonists applied by microiontophoresis to bulbar respiratory neurones were determined in different preparations: cats anaesthetized by pentobarbital and immobilized by gallamine triethiodide, intercollicular decerebrate cats either not immobilized or immobilized by gallamine triethiodide. Respiratory neurones located at the bulbar level exhibited a muscarinic cholinergic sensitivity in all preparations. Muscarinic responses were either excitatory or inhibitory. The number of neurones showing excitatory responses was lower under pentobarbital anaesthesia than in decerebrate cats.

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Morin-Surun, M.P., Champagnat, J., Denavit-Saubie, M. et al. The effects of acetylcholine on bulbar respiratory related neurones. Naunyn-Schmiedeberg's Arch. Pharmacol. 325, 205–208 (1984). https://doi.org/10.1007/BF00495944

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  • DOI: https://doi.org/10.1007/BF00495944

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